O-Acetyl-L-carnitine Hydrochloride Protein Peptide Hormones CAS 2627-69-2

CAS 2627-69-2 O-Acetyl-L-carnitine Hydrochloride Protein Peptide Hormones Aicar Acadesine For Shaping

Quick Detail:

Name: Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 98%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

Description:

AICAR uses metabolic pathways to block certain enzymes, which allows for AMP-activated protein kinase. This can be explained to the layperson like this: once you take a substantial amount of AICAR, it tricks your body at a cellular level in to thinking that exercise has just been performed. Since the body thinks it has just done a considerable amount of exercise, the energy cycle at the cellular level starts converting fuel sources, like fatty acids, to output the energy that was thought to have been spent during exercise. This can have a direct effect on the level of endurance activity and the sustainability of that activity. Insulin sensitivity is also noted to be one action that AICAR produces, as the body will think it just went through a series of exercises. Interestingly, in animal studies with obese mice, AICAR showed all of the peptides benefits for obese diet induced mice, yet the healthy lean mice did not reap any of the benefits of insulin sensitivity or increase in glucose uptake. That being said, the application in bodybuilding does not seem very suitable, as these mechanisms are targeted for the out-of-shape and overweight, so if you are not a top level endurance athlete I just do not see the reason for using AICAR. A much better option would be Cardarine (GW-50156), as this compound is readily activated by exercise, so the need to work out or cardio would be an incentive.

Specification:
 

Function:

AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).

AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

Application:

(1) Aicar applied in phamaceutical field, it is used as phamaceutical raw material to treat injuries from fall, infectious hepatitis and epidemic cerebrospinal meningitis.
(2) Aicar applied in healthcare field, it is used in the health products to nourish brain, protect liver and improve sleep quality.
(3) Aicar applied in cosmetics field, it is used to promote skin metabolism and make skin more tender and firm.

Peptide lists and each usage:
 

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